Lister Unified Communications has teamed up with Punchline-Gloucester.com to encourage Gloucestershire businesses and residents to recycle their old phones, with proceeds going to The Nelson Trust.
The Stroud-based charity brings hope and long-term recovery to lives affected by addiction and multiple disadvantages.
The old phones either get refurbished and upcycled or broken down, as their parts contain tiny parts of precious metals.
Mobile phone recycling bins have been placed in the county's six Growth Hubs - in Gloucester, Cheltenham, Stroud, Cirencester, Tewkesbury and Mitcheldean.
A growing number of businesses have also come on board to support the campaign, including the Spirax Group, Cass Stephens, Forest Green Rovers and Enterprise Mobility.
Research by Giffgaff indicates that more than 100 million unused devices, worth a collective £14.1 billion, are gathering dust in houses. On average, each UK adult possesses at least two unused mobile devices at home, with another two devices having been discarded in the bin. Despite the potential value, many end up in landfill sites.
Punchline-Gloucester.com editor Mark Owen said: "Our mission is to get as many businesses as possible in the county to join this campaign. There's momentum building as more and more people come on board, but we're looking for more people to get involved. We're appealing to businesspeople to encourage their staff to recycle their phones.
"We've collected over 2,500 mobile phones so far, but we want more people to collect them, because we've only just really scratched the surface. We need somebody to be a champion at work who can ask their colleagues or their families to collect mobile phones.
"My wife's auntie went to her parish church and collected 20 phones. If everybody did that, we could collect thousands of phones. So if you have an old mobile phone, just take it to The Growth Hub and help make a difference. Or even better, put a box in your workplace and put everyone's old phones in there, and get in touch with The Nelson Trust to arrange collection."